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Their decline aligns with the reduction of total nitrogen (4.76% to 3.62%) and nicotine (3.25% to 2.93%) in Figures 1D,E, suggesting microbial catabolism of amino acid precursors into volatile aroma compounds (e.g., phenylacetaldehyde)

likewise, the Cochrane review also indicated the efficacy of bupropion for individuals who smoke who have schizophrenia, despite the presence of adverse effects such as headache, dry mouth, and insomnia [6, 11, 50]

The Ordinance made a similar distinction between citizens and non-citizens for candidates for election to the territorial legislature

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