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Most adults view tobacco cigarettes as harmful now, and that's led to fewer smokers as role models and fewer families where smoking is deemed okay

It comes in a small and candy-like tablet with a variety of flavours, taken orally and allowed to dissolve in the mouth for the nicotine to be absorbed into the bloodstream

Additionally, racial/ethnic differences in nicotine metabolism have been well-established, with non-Hispanic Black (NHB) smokers exhibiting higher serum cotinine levels despite smoking fewer cigarettes per day compared to non-Hispanic White (NHW) smokers 3-6

Spice has caused many serious cases of intoxication requiring intensive care, and some fatal cases have been described