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occasional use, nicotine concentration), making it difficult to assess the cumulative effects of vaping on COPD risk

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Of the $9 billion in revenue that e-cigarettes and vaping products are expected to generate in the United States by the end of 2019, about $6.4 billion (72%) will come from physical locations like convenience and drugstores, while $2.6 billion (28%) will be generated online and at other sources, according to a March research report by Wells Fargo Securities

Discussion The observed difference in the number of cigarettes smoked was in the hypothesised direction, with fewer cigarettes smoked per day in the intervention arm (pack sizes of 20 cigarettes) than the control arm (pack sizes of 25 cigarettes)