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44 In addition, in BC xenograft mouse models, a reduction in tumor growth rate and metastasis, combined with decreased TAM infiltration, was observed when they were treated with macrophage-targeting chemotherapy (trabectedin) or CSF1 inhibitors, which highlighted a potential therapeutic opportunity

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Results Tectonic geomorphology The tectono-geomorphic characterization and earthquake focal mechanism analyses target key structural domains of eastern Indonesia, including the Birds Neck and Birds Head of New Guinea, the BuruSeram archipelago, the Cenderawasih Bay margin, the Aru Trough, the Kei Islands region, and adjacent deep basins such as the Weber Deep, which are presented in the following sections (Figs