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The study established that FOXO4 maintains senescent cell viability by targeting p53 to the nucleus and preventing apoptosis, and that disrupting the FOXO4-p53 interaction with FOXO4-DRI causes p53 nuclear exclusion and cell-intrinsic apoptosis in ionising radiation-induced and doxorubicin-induced senescent IMR90 fibroblasts

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BPC-157 is notably stable across a wider range of pH and temperature conditions than many comparable research peptides, which has practical implications for storage and handling

It was conducted at Seoul National University (one of Asia's top research institutions) with full IRB ethical approval