main purpose Receptor binding and activation of signaling pathways IGF-1 LR3 activates two main downstream signaling pathways by binding to the IGF-1 receptor (IGF-1R): PI3K/Akt pathway: promotes cell survival, glucose metabolism, and protein synthesis
92, 561564 10.1111/1523-1747.ep12709572 [DOI] [PubMed] [Google Scholar] 44.Cardinali G., Bolasco G., Aspite N., Lucania G., Lotti L.V., Torrisi M.R.et al
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