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While working as a teacher in Isleworth, west London, aged 23, his landlady Annie Slade-Jones complained about the smell of his smoking

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Acknowledgements The author would like to acknowledge the contributions of Patrick Goegan and Sara Rumbolt (Health Canada) and Alison Savage (US Environmental Protection Agency), as well as NCCEH staff Sarah Henderson, Lydia Ma, and Michele Wiens

Participation involved additional blood taken for EPF with the 2-h glucose tolerance test (75 g oral glucose load administered after an overnight fast) at 2426 weeks gestation and EPF studies on umbilical cord blood at delivery