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Preliminary data in plasma suggest an increase in circulating pro-inflammatory cytokines in e-cigarette users

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However, PINK1 overexpression did not enhance CSE-induced mitophagy or restore the mitophagy impairment caused by PRKN knockdown, suggesting that PRKN protein levels may be the primary rate-limiting factor in PINK1/PRKN-mediated mitophagy ( Although the PINK1/Parkin pathway is generally regarded as the dominant mechanism regulating mitophagy, mitophagy can still be maintained in the absence of PINK1 or Parkin

She was more than 6,000 miles away in Monaco at the training camp ahead of the Olympics starting on 26 July