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Toxicological Assessment In the USP nicotine monograph, a limit of 0.3% relative to nicotine target is listed for each of nornicotine, anatabine, anabasine, cotinine, nicotine- N -oxide, myosmine, and -nicotyrine, indicating that this level is considered tolerable for minimizing health risks from these compounds

Nighbor TD, Doogan NJ, Roberts ME, Cepeda-Benito A, Kurti AN, Priest JS, et al

The next step, she said, would be to work with clinicians who provide behavioral therapy for smoking cessation

They have established certain regulations restricting devices like vape pens, electronic cigarettes, and other accessories from being transported through planes