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Our study shows that nicotine binds to the enzyme responsible for the synthesis of estrogen in the thalamus the brain region with the highest expression of this enzyme and of receptors for nicotine. Comasco said her team was surprised by how powerful nicotine was on areas of the brain targeted by addictive substances and added that they arent yet sure what the behavioral or cognitive outcomes are

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The four-year study, titled Evaluating Cigarette Relighting Behavior: Prevalence, Correlates, Toxicant Exposure, and Implications for Cessation, will look at a variety of factors in over 6,000 adults ages 21 and older throughout the United States