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Nature 342 , 440443 (1989)

Starting condition: Right shoulder impingement from years of pressing (overhead press hurt, bench press was uncomfortable, even lateral raises caused issues) Post-workout stiffness lasting 48-72 hours minimum Gut problems: bloating after most meals, unpredictable bathroom schedule, general digestive discomfort Training frequency limited by recovery capacity The protocol: One 500mcg capsule first thing in morning (empty stomach) One 500mcg capsule before bed (2+ hours after last meal) Zero other variables changed: same training split, same nutrition, same sleep schedule Tracked shoulder range of motion, post-workout soreness duration, digestive symptoms Week 1: Nothing

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However, this side effect is not common and can be minimized by consulting with your physician on prescribing right injection dose