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Most e-cigarettes consist of four different components, including: a cartridge or reservoir, which holds a liquid solution (e-liquid or e-juice) containing varying amounts of nicotine, flavorings, and other chemicals a heating element (atomizer) a power source (usually a battery) a mouthpiece that the person uses to inhale In many e-cigarettes, puffing activates the battery-powered heating device, which vaporizes the liquid in the cartridge

Cigarettes cause most of their damage by burning tobacco and producing tar and other byproducts, and pouches and vapes skip that entirely

Exosomes and microvesicles (EMV) are associated with tumor spread and chemotherapy resistance, through expelling drugs outside the cancer cells (Liu and Wang 2023)