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A study published in JAMA Internal Medicine in 2014 concluded: E-cigarette use by smokers was not followed by greater quitting, or reduction in consumption one year later. Another 2015 study in the journal Addiction found that daily use of e-cigarettes seemed to be associated with an increase in the rate of attempts to quit smoking and less smoking, though not increased rates of quitting

It is a close relative to the deadly nightshade that can only be found in the Americas

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In severe cases, an overdose of depressants can result in respiratory depression, coma, and death