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A pesar de ello, la toxicidad cutnea que presentan algunos de los nuevos frmacos supone un obstculo para los onclogos a la hora de completar, a las dosis ptimas, algunos de los protocolos de quimioterapia ms recientes

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Sci Tot Environ 94:7187 Beach GB, Quilliam MA, Rouleau C, Croll RP, Hellou J (2010) Bioaccumulation and biotransformation of pyrene and 1-hydroxypyrene by the marine whelk Buccinum undatum