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Bibcode:2020NatCo..11.5978G

Introduction More than 7,000 chemical compounds (constituents) have been identified in cigarettes and cigarette smoke,[1] at least 69 of which are known carcinogens.[2] In addition to cancer, cigarette smoke chemicals also cause cardiovascular, respiratory, reproductive, and developmental problems.[3] Smokers have heard of relatively few of these chemicals but have an interest in learning more about them.[4, 5] The 2009 Family Smoking Prevention and Tobacco Control Act requires the US Food and Drug Administration (FDA) to produce a list of harmful and potentially harmful chemicals in cigarette smoke