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Finally, we highlight emerging therapeutic strategies aimed at rewiring TAM metabolism or exploiting ferroptosis to overcome immune suppression and therapy resistance

3-AR knockout mice: In 3-AR gene knockout mice, the lipolysis effect of AOD 9604 was significantly weakened, confirming that its effect depends on the 3-AR signaling pathway

Primary hepatocytes were seeded in 12-well plates and transduced with Hmox1 -shRNA adenoviruses for 24 h before any additional treatment

Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development