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Our results show that SPT reduces the number and diameter of secondary follicles while increasing atretic follicles, underscoring the adverse effects of metabolic stress on follicular development

cerevisiae was utilized to keep uniform expression of each construct in this work

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Due to the secretion of signalling molecules and cytokines, the cross-talk between microglia and astrocytes is enhanced, which can lead to vascular-endothelial dysfunction and damage to bloodbrain barrier (BBB) permeability