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reported that the low GSH production of permeated cells immobilized using a polyacrylamide gel was caused by the low efficiency of the ATP supply: only 0.5 % of the total regenerated ATP from the glycolytic pathway was actually used for GSH synthesis in E

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902 All P-type ATPases possess three domains, a transmembrane domain (TM) composed of six to eight membrane-spanning -helices that comprise the transport channel, an ATP-binding domain composed of nucleotide (N) binding and phosphorylation (P) subdomains, and an actuator domain (A) that allosterically signals a change in the phosphorylation status in the P domain to the TM domain to allow for transport

Virz GM, Mattiotti M, Clementi A, Milan Manani S, Battaglia GG, Ronco C, et al