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Our study confirmed that SFN can be effective against cutaneous inflammation in an IMQ-induced psoriatic mouse model, consistent with previous findings of its therapeutic effects in chronic inflammatory diseases such as inflammatory bowel disease, respiratory diseases, and rheumatoid arthritis [35]

Overall prevalence is 1 in 30,000, and around 1 in 90 people are carriers of the defective gene[2,4]

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While the importance of filamentation and candidalysin has been confirmed in a wide variety of infection models 3,7,43,44,45 , the low ex vivo pathogenincity of clinical isolates from infections contradicts this dogma