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We used 353 independent single-nucleotide polymorphisms associated with cigarette smoking initiation as instrumental variables at genome-wide significance threshold ( p 0.1), leaving 353 independent instrumental variables for smoking initiation

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Advocates say the goal is to make it harder for children and teens to become addicted to nicotine by banning the sale of sweet flavors that appeal to them

In recent years, however, increasing evidence supports dysfunction of the glutaminergic system as being the primary pathophysiological changes seen in schizophrenia [105]