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Although PFTs are essential for diagnosing and monitoring disease, their accuracy depends heavily on patient effort (often incomplete), technician skill (frequently inconsistent in enforcing a maximal effort, correct posture, a tight mouth seal and nose clip, or other protocolised minimums), and precise equipment handling

The demands the FDA places on companies filing these applications are so extraordinary difficult to meet that only those with huge resources and personnel _ in terms of scientists, lawyers, researchers _ are able to file successfully, said Warner

[DOI] [PubMed] [Google Scholar] Gazdzinski S, Durazzo TC, Studholme C, Song E, Banys P, Meyerhoff DJ

Smoking is allowed in the outdoor public areas, 25 feet from any building entrance