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Direct Smoking Tests Perhaps the most visually shocking type of tobacco testing are the direct smoking tests, made famous in 1975 by undercover Sunday People reporter Mary Beith in her expose known as The Smoking Beagles. Beith got a position in an Imperial Chemical Industries laboratory where 48 beagles were restrained with straightjackets, placed into what Beith described as medieval stocks and fitted with tubed masks which forcibly pumped cigarette smoke into their lungs day in and day out for up to three years for some of the dogs

Primack BA, Bost JE, Land SR, Fine MJ

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With more and more states legalizing marijuana for recreational use, that number is likely to continue going up