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We describe the optimization of three additional approaches to toxicant reduction (split-tipping, smaller cigarette circumference, and increased carbon filter length and loading), their combination within a new RTP, and comparison between the performance of this cigarette and that of a relevant commercial product

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Remarkably similar patterns are occurring in the US, with overall nicotine product use slightly declining over time, and (within this) a massive shift away from cigarettes and towards e-cigarettes, especially in younger age groups

More research is urgently needed to examine the association between e-cigarette use and psychosis, particularly in adolescents and young adults, Dr Scott said