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It is important to draw attention that most of the erythrocytes might be exposed to such harsh treatment over and over again in its life span of 120 days producing a cumulative surface damage

The long-term effects of smoking include: Cancer Heart disease Stroke Lung disease Diabetes Chronic obstructive pulmonary disease (COPD) Emphysema Chronic bronchitis Tuberculosis Eye disease Rheumatoid arthritis Immunocompromised How Smoking Affects Your Heart and Blood Vessels Risks of smoking also include cardiovascular complications

Method #4