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This combination may be particularly valuable for patients who have reached a weight loss plateau despite good surgical anatomy, or those with persistent insulin resistance and type 2 diabetes despite significant weight loss

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It will be much safer if people can get these compounds through state-regulated compounding pharmacies

Acknowledgements This work was supported by grants from the National Institute of Health (NIH R01HL145031 for ZI, NW, RS, LB, MLY, J.PA., OBU and NIH R21GM136002 for MLY and OBU) and National Science Foundation (NSF EEC-1941543 for ZI, EC, MLY, OBU)