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The treatment disrupted lipid raft integrity in cell membranes, thereby perturbing critical downstream signaling pathwaysincluding PI3KAKTmTOR and Wnt-cateninand reprogramming the expression of oncogenic genes such as c-Myc

This approach is particularly valuable given the difficulties in regenerating amaranth after transformation ( 7.2 Propagation of regenerated plantlets In addition to transformation, in vitro propagation of transgenic amaranth plantlets is necessary to obtain stable lines

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Common triggers include citrus fruits, tomato products, spicy foods, chocolate, caffeine, and alcohol, though individual sensitivities vary significantly