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Description

First, direct pharmacological interactions where one compound changes how another works in the body

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In addition, IONIS-DGAT2 Rx , an ASO targeting diacylglycerol acyltransferase 2 (DGAT2, an enzyme that catalyzes the final step in TG synthesis in the liver), improved liver steatosis in patients with NASH in phase 2 clinical trial (NCT03334214)