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Depression is one of the most prevalent mental health disorders globally, affecting over 280 million individuals and significantly impacting academic, social, and occupational functioning ( The link between depression and the consumption of psychoactive substances, such as tobacco and caffeine, has been widely studied

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Ben Affleck, 52, recreates the viral sad-Affleck smoking meme while seeming miserable during a smoke break from shooting his new film Animals in Los Angeles on Friday

[58] Additionally, there is little disapproval for the use of e-cigarettes among adolescents