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When heated as part of a cannabis concentrate formulation via certain methods of dabbing, they can degrade to produce toxins. While the discovery of the relationship between terpenes and carcinogens may be a new development, others say that finding benzene and other toxic substances in BHO should be expected

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A 2021 review found people who used e-cigarettes to quit smoking, as well as having expert face-to-face support, can be up to twice as likely to succeed as people who used other nicotine replacement products, such as patches or gum