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Additionally, treatment with 5-HT 2C antagonists enhances ghrelin-induced food intake, whereas treatment with lorcaserin, a 5-HT 2C agonist, decreases ghrelin-induced food intake (Schellekens et al., 2015)

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Ipamorelin is a growth hormone secretagogue that activates the ghrelin receptor (GHS-R1a) a completely separate pathway that is synergistic with GHRH receptor activation

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IGFBP-3 is the major IGF-I binding protein

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Biological & Pharmaceutical Bulletin, 44 (12), 18321836

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