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In this nationwide population-based nested case-control study of nearly 1,000 schizophrenia subjects, we demonstrated an association between maternal nicotine exposure, quantified as cotinine during gestation, and schizophrenia in offspring, the researchers write

(Like, get ready for a whole new lease on air travel!) So many young people that weve spoken to over the past five years say, This was the hardest thing I've ever done, and now I feel like I can do anything, Jacobs says

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These differential effects align with knowledge based on animal studies that nAChR subunits contribute to distinct aspects of smoking behavior 8,17