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4e), whereas state B expressed more SMG secretory markers, potentially marking the former as a basal cell state initiating differentiation and the latter as a state committed to a secretory fate

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The inter-rater reliability was high across all codes, with the agreement ranging from 86% to 99%, and prevalence-adjusted and bias-adjusted kappa (PABAK) statistic ranging from 0.72 to 0.97 with an average of 0.89 (Supplementary file Table 1)

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