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The drug hydroxyurea (Hydrea), which is often used to treat painful crises in sickle cell anemia, may be of benefit in some thalassemia patients (Rund 2005)

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Cytosolic cysteine comes from only three sources: (1) from methionine via the methionine cycle and the transsulfuration pathway, (2) direct import into the cell from the plasma, and (3) from excess protein catabolism over protein synthesis