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The prevalence of ever vaping was highest in young adults aged 2024 years, at 43%, while youth aged 1519 years had a prevalence of 35% 2

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In an important study by Khokhar and Tyndale, the authors found that 7 days of nicotine treatment increased CYP2B expression in the brain, but not liver, and surprisingly, this change in metabolism was sufficient to potentiate the sleep-inducing effects of the general anesthetic propofol in male rats (167)