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[154] Acting style and legacy [edit] Keaton has been said to be "one of the great American actresses from the heyday of the 1970s", a style icon and a "treasure" with a personal and professional style that is "difficult to explicate and impossible to duplicate." [155] [156] [157] Many critics have pointed to her versatility in starring in both light comedies and acclaimed dramas

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Nicotine has been shown to increase the mRNA expression of amyloid precursor protein in the amygdala and hippocampus (Gutala et al., 2006)

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