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For example, for a pouch containing 8 mg of nicotine, only 32% of the nicotine was released after 60 minutes of use.*4 A second test in the same study confirmed this about 33% for a Swedish snus pouch with the same nicotine content (8 mg/pouch).*5 So, in that Swedish study, a snus pouch with 8 mg of nicotine released around 2.5 mg after 60 minutes and this forms the basis for the actual nicotine the body can absorb

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Association of long-term, low-intensity smoking with all-cause and cause-specific mortality in the National Institutes of Health-AARP diet and health study