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Methods: We commissioned systematic reviews on evidence of benefits and harms of smoking cessation interventions in adults, comprising an overview of Cochrane reviews on behavioural interventions, pharmacotherapy, and other interventions, and a systematic review on electronic cigarettes (e-cigarettes)

Uncomplicated in this context means the patient meets criteria for opioid dependence but does not currently present with withdrawal, intoxication, or other coded complications at the time of the encounter

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