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Additionally, we predicted that smokers with depressive symptoms may be more likely to be motivated to quit cigarette smoking, as found previously;9 however, we were uncertain whether cannabis use would moderate the effects of depression for each of the outcomes

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Second, and more importantly, during the weeks following the intervention, larger decreases in cigarette use were seen in stress versus control group participants

According to Youth.gov, most adults who have a substance use disorder started using before age 18 and develop the disorder by age 20. The use of any substance can alter neural pathways that are developing in the adolescent brain