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Both the DJ-1 and LRRK2 proteins are associated with the autophagy-lysosome pathway, maintaining a role in mitochondrial and lysosomal function while being essential for maintaining normal cellular function and survival (Lizama and Chu, 2021)

Intervention group ( n = 10), free drink 0.2% lead acetate solution, and 1 mL folic acid (Sigma-Aldrich) suspension was intragastrical administered (prepared according to the dose of 0.4 mg/kg BW folic acid)

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When re-introduction of HA-ATG2A or HA-ATG2A-3CS into these cells restored the ratio, overexpression of ZDHHC11 inhibited the effect of HA-ATG2A but not that of HA-ATG2A-3CS (Fig