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Chronic exposure of the lungs to cigarette smoke disrupts the mitochondrial activity and endoplasmic reticulum (ER) homeostasis that triggers an unresolvable unfolded protein response activation

Implementing comprehensive school smoking policies, such as smoke-free school hours, along with teacher empowerment workshops, smoke-free campus programs, and policies, can contribute to preventing and reducing cigarette use among young people in high-risk school settings 29