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You'll need to take vitamin B12 injections depending on your situation if your deficiency is not diet-related

The first cardiovascular study of NNMT enzyme inhibition in a heart failure with preserved ejection fraction (HFpEF) mouse model demonstrated that treatment markedly reduced 1-MNA (by 77.1%), 2PY (by 66.2%), and 4PY (by 71.1%) in cardiac tissue, while improving cardiac function, enhancing global longitudinal strain, reversing peak longitudinal strain rate, and significantly reducing left ventricular hypertrophy and fibrosis

Research/educational use only, not medical advice

Before receiving folic acid or cyanocobalamin, patients should be assessed for deficiency and appropriate therapy started concurrently