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For patients receiving B12 replacement therapy for pernicious anaemia or deficiency , monitoring is typically arranged by the prescribing clinician

The most commonly reported side effects are mild and transient: injection site redness or minor bruising, transient fatigue in the first one to two weeks, and occasionally mild headache following the first few injections, a pattern sometimes attributed to the acute shift in cellular energy metabolism as AMPK pathways are upregulated [3]

Load-bearing capacity improves post-recovery