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By reducing the burden of senescent cells, Fisetin may improve cellular health, delay the onset of ageing-related conditions, and support longevity

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However, when viral infection, environmental stress, or immunosuppression impairs these defenses, microbes from the oral cavity and URT can aberrantly colonize the LRT, markedly increasing the risk of BRD through pathogenic mechanisms and microbial agents similar to those described in the URT section above

Furman, J