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While no information was given regarding formaldehyde and acetaldehyde concentrations, the authors calculated that one puff could result in an acrolein exposure of 0.0030.015 g/mL [4]

Chewing releases these aromas, which then activate the sense of smell

In a subsequent study, these investigators reported that, in contrast, acute, nose-only continuous exposure of male Sprague-Dawley rats to the smoke of one, two, or four unfiltered 1R1 reference cigarettes produced smaller reductions in catecholamine levels and increases in catecholamine turnover and did not produce an increase in dopamine utilization in the median eminence (Andersson et al