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For long-term studies, it is highly recommended to aliquot the stock solution into single-use volumes in sterile microcentrifuge tubes and store them frozen at -20C or -80C

In the Parkinson disease, most part of the works has shown there are free radicals increase, mainly in the brains nucleus that will produce L dopa and are mainly cytotoxins and neurotoxins, that cat at this level increasing the superoxide production (Halliwell and Guteridge

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This raises the oxidative injury in lipid peroxidation which enhances the lethal impacts of these treatments, enhancing their effectiveness [16]