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Nickel S et al (2016) Transport mechanisms at the pulmonary mucosa: implications for drug delivery

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It is also predicted that elevated PM 2.5 and rising ozone concentrations would intensify the effects of PM 2.5 .During phagocytosis, the particle buildup in macrophages might ultimately lead to the initiation of pro-inflammatory pathways, a phenomenon known as frustrated phagocytosis, with long-term exposure (158)

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