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Pregnancy and Pre-existing Conditions As with any supplement, those who are pregnant, breastfeeding, or managing a diagnosed medical condition should consult a healthcare professional before starting

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[176] Prolonged elevations of brain temperature above 40 C likely promote the development of amphetamine-induced neurotoxicity in laboratory animals by facilitating the production of reactive oxygen species, disrupting cellular protein function, and transiently increasing bloodbrain barrier permeability

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