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Most of this spending is on price discounting schemes, which undermine tobacco tax increases and make tobacco products more affordable for price-sensitive kids

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Aging is associated with increasing DNA damage, and the repair machinery, containing DNA methyltransferases and the Polycomb repressive complex, appears to favor CpG-rich regionsincluding the ones we refer to as Polycomb targetsas substrates for de novo methylation [99, 110]

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