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The nicotine and chemicals used in vaping can also cause the breakdown of collagen a protein that helps to keep our skin firm and plump which is why smokers and vapers often develop lines around the lips and have puffiness around their eyes." Nicotine acts as a vasoconstrictor, meaning it causes the narrowing of small blood vessels, which reduces oxygen supply and the flow of nutrients to the skin, Dr Patterson explains

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A visual summary of the guideline is available in Figure 1

This album's distinctive fusion of lively and quiet music demonstrates the artist's versatility and talent