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Follow-up of treatment: this period consolidates the cessation of smoking and begins nicotine withdrawal Therapeutic Withdrawal: This period should allow you to stop treatment

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Studies of this smoking-thrombolysis paradox have shown that TS use is associated with reduced infarct growth, as well as a higher rate of recanalization and reperfusion in TS users treated with IV r-tPA, following ischemic stroke (Kufner et al., 2013)

In this situation, a modified, very low dose of varenicline 0.250.5 mg per day could be used under close observation